All Curated Mutation Sites in HBV

The VM annotation module provides researchers who are interested in VMs with annotations of reported pathogenic mutations in HBV related to human diseases easily. The curated mutation information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region or Disease

*Please select one option you are interested in, the page will be automatically redirected.

Virus Gene/Protein/Region:

Disease:

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	19272629	P110S	PreS1	D G R CI C	View
2	18713056	S5T	PreS1	D G R S	View
3	19889143	A6D	PreS1	G R S C	View
4	19889143	F7S	PreS1	G R S C	View
5	19889143	G10S	PreS1	G R S C	View
6	19889143	G2R	PreS1	G R S C	View
7	19889143	G5Q	PreS1	G R S C	View
8	19889143	L3I	PreS1	G R S C	View
9	19889143	L8*	PreS1	G R S C	View
10	19889143	M1I	PreS1	G R S C	View
11	19889143	S4P	PreS1	G R S C	View
12	19889143	W5R	PreS1	G R S C	View
13	19889143	N98Y	PreS1	G R S C	View
14	19889143	S109P	PreS1	G R S C	View
15	19889143	S16P	PreS1	G R S C	View
16	19889143	F23S	PreS1	G R S C	View
17	19889143	D26Y	PreS1	G R S C	View
18	19889143	D41N	PreS1	G R S C	View
19	19889143	P88L	PreS1	G R S C	View
20	19889143	A89T	PreS1	G R S C	View
21	19889143	P93L	PreS1	G R S C	View
22	19889143	R102G	PreS1	G R S C	View
23	19889143	T105I	PreS1	G R S C	View
24	19889143	P106S	PreS1	G R S C	View
25	20119580	A81T	PreS1	G R CI C	View
26	20119580	A91T	PreS1	G R CI C	View
27	20119580	A95T	PreS1	G R CI C	View
28	20119580	A95V	PreS1	G R CI C	View
29	20119580	G2A	PreS1	G R CI C	View
30	20119580	G73D	PreS1	G R CI C	View
31	20119580	I84T	PreS1	G R CI C	View
32	20119580	L74I	PreS1	G R CI C	View
33	20119580	T86A	PreS1	G R CI C	View
34	20119580	V60A	PreS1	G R CI C	View
35	21785721	T361A	PreS1	G R S C	View
36	23029487	F25L	PreS1	R S CI C	View
37	23029487	I48T	PreS1	R S CI C	View
38	23029487	I48V	PreS1	R S CI C	View
39	23029487	V88A	PreS1	R S CI C	View
40	23029487	V88L	PreS1	R S CI C	View
41	27182775	3014_3198 DEL	PreS1	G R S C	View
42	27182775	3046_3177 DELETION	PreS1	G R S C	View
43	27182775	3115_3123 DELETION	PreS1	G R S C	View
44	31046787	G2765A	PreS1	G R S C	View
45	31046787	T2768G	PreS1	G R S C	View
46	31046787	T2768A	PreS1	G R S C	View
47	31046787	T2780C	PreS1	G R S C	View
48	31046787	C2771T	PreS1	G R S C	View
49	15834874	C3026T	PreS1	G S C	View
50	15834874	A60V	PreS1	G S C	View
51	19574418	T31C	PreS1	G S C	View
52	19574418	T53C	PreS1	G S C	View
53	20419326	A2964C	PreS1	G S C	View
54	24632784	R34K	PreS1	G S C	View
55	26890489	F25L	PreS1	S CI C	View
56	26997220	D16E	PreS1	G S C	View
57	26997220	T40P	PreS1	G S C	View
58	26997220	F56L	PreS1	G S C	View
59	26997220	Q75H	PreS1	G S C	View
60	26997220	L77R	PreS1	G S C	View
61	26997220	Q107K	PreS1	G S C	View
62	26997220	W111SC	PreS1	G S C	View
63	27486882	128-131 DEL	PreS1	G R C	View
64	27486882	G91A	PreS1	G R C	View
65	27486882	I255T	PreS1	G R C	View
66	27486882	S98T	PreS1	G R C	View
67	27486882	N310D	PreS1	G R C	View
68	27486882	T114I	PreS1	G R C	View
69	27486882	T119P	PreS1	G R C	View
70	27486882	N103D	PreS1	G R C	View
71	27651827	A35E	PreS1	G S C	View
72	27651827	H44L	PreS1	G S C	View
73	27651827	K13E	PreS1	G S C	View
74	27651827	N29K	PreS1	G S C	View
75	27651827	R38K	PreS1	G S C	View
76	27651827	S90T	PreS1	G S C	View
77	27651827	V80I	PreS1	G S C	View
78	28859616	A2962G	PreS1	G S C	View
79	28859616	C2964A	PreS1	G S C	View
80	28859616	C3026A	PreS1	G S C	View
81	28859616	C3026T	PreS1	G S C	View
82	28859616	N38E	PreS1	G S C	View
83	28859616	N38K	PreS1	G S C	View
84	28859616	A60V	PreS1	G S C	View
85	28859616	A60E	PreS1	G S C	View
86	29642827	A33T	PreS1	G S C	View
87	29642827	A39T	PreS1	G S C	View
88	29642827	A81S	PreS1	G S C	View
89	29642827	A90T	PreS1	G S C	View
90	29642827	A90V	PreS1	G S C	View
91	29642827	A95P	PreS1	G S C	View
92	29642827	44 DELD	PreS1	G S C	View
93	29642827	D50N	PreS1	G S C	View
94	29642827	D54N	PreS1	G S C	View
95	29642827	F67L	PreS1	G S C	View
96	29642827	I84T	PreS1	G S C	View
97	29642827	L65M	PreS1	G S C	View
98	29642827	L65P	PreS1	G S C	View
99	29642827	L85I	PreS1	G S C	View
100	29642827	L85M	PreS1	G S C	View
101	29642827	L88S	PreS1	G S C	View
102	29642827	N114D	PreS1	G S C	View
103	29642827	N114E	PreS1	G S C	View
104	29642827	91 DELN	PreS1	G S C	View
105	29642827	N91K	PreS1	G S C	View
106	29642827	N98K	PreS1	G S C	View
107	29642827	P110S	PreS1	G S C	View
108	29642827	P41K	PreS1	G S C	View
109	29642827	Q100K	PreS1	G S C	View
110	29642827	Q82E	PreS1	G S C	View
111	29642827	Q86H	PreS1	G S C	View
112	29642827	Q86T	PreS1	G S C	View
113	29642827	S101T	PreS1	G S C	View
114	29642827	S109T	PreS1	G S C	View
115	29642827	S96A	PreS1	G S C	View
116	29642827	T51P	PreS1	G S C	View
117	29642827	T97A	PreS1	G S C	View
118	29642827	T97I	PreS1	G S C	View
119	29642827	W77T	PreS1	G S C	View
120	30835025	S17A	PreS1	G R C	View
121	31501793	A49V	PreS1	G R C	View
122	31501793	K38R	PreS1	G R C	View
123	31501793	L11Q	PreS1	G R C	View
124	31501793	N37S	PreS1	G R C	View
125	31501793	M1T	PreS1	G R C	View
126	31501793	T5P	PreS1	G R C	View
127	31501793	T5A	PreS1	G R C	View
128	31501793	G29A	PreS1	G R C	View
129	31501793	L19*	PreS1	G R C	View
130	31501793	N32D	PreS1	G R C	View
131	31952213	C2964A	PreS1	G R C	View
132	31952213	C3062T	PreS1	G R C	View
133	32532295	T3098C	PreS1	G S C	View
134	32532295	C3026T	PreS1	G S C	View
135	32532295	C3121A	PreS1	G S C	View
136	32532295	C3189A	PreS1	G S C	View
137	32532295	A49V	PreS1	G S C	View
138	32532295	I73T	PreS1	G S C	View
139	32532295	P81T	PreS1	G S C	View
140	32532295	D103E	PreS1	G S C	View
141	10534721	G61S	PreS1	G C	View
142	10534721	Q75H	PreS1	G C	View
143	12805468	A119F	PreS1	S C	View
144	16227269	A119F	PreS1	CI C	View
145	17258721	L8R	PreS1	G R	View
146	17258721	D42E	PreS1	G R	View
147	17258721	W43G	PreS1	G R	View
148	17258721	P65A	PreS1	G R	View
149	17258721	A62S	PreS1	G R	View
150	17258721	P53R	PreS1	G R	View
151	17258721	R113K	PreS1	G R	View
152	17258721	N56D	PreS1	G R	View
153	17258721	W43R	PreS1	G R	View
154	17258721	N46D	PreS1	G R	View
155	17258721	P53A	PreS1	G R	View
156	17258721	N56I	PreS1	G R	View
157	17258721	N56S	PreS1	G R	View
158	17258721	F63V	PreS1	G R	View
159	17503077	L49R	PreS1	G C	View
160	17503077	V14A	PreS1	G C	View
161	17825452	Q86H	PreS1	G R	View
162	17825452	T86H	PreS1	G R	View
163	17825452	A86H	PreS1	G R	View
164	17825452	K86H	PreS1	G R	View
165	17825452	K10Q	PreS1	G R	View
166	17825452	L10Q	PreS1	G R	View
167	17825452	R10Q	PreS1	G R	View
168	17825452	S38P	PreS1	G R	View
169	17825452	T38P	PreS1	G R	View
170	17825452	Q38P	PreS1	G R	View
171	17825452	N39D	PreS1	G R	View
172	17825452	A39D	PreS1	G R	View
173	17825452	R39D	PreS1	G R	View
174	17825452	S39D	PreS1	G R	View
175	17825452	E39D	PreS1	G R	View
176	17825452	P65R	PreS1	G R	View
177	17825452	Q65R	PreS1	G R	View
178	17825452	L65R	PreS1	G R	View
179	17825452	G66D	PreS1	G R	View
180	17825452	T68L	PreS1	G R	View
181	17825452	P68L	PreS1	G R	View
182	17825452	P69H	PreS1	G R	View
183	17825452	L69H	PreS1	G R	View
184	17825452	S101L	PreS1	G R	View
185	17825452	N46I	PreS1	G R	View
186	17825452	T46I	PreS1	G R	View
187	17825452	H51I	PreS1	G R	View
188	17825452	T51I	PreS1	G R	View
189	17825452	S51I	PreS1	G R	View
190	17825452	P51I	PreS1	G R	View
191	17825452	N51I	PreS1	G R	View
192	17825452	G73A	PreS1	G R	View
193	17825452	D73A	PreS1	G R	View
194	17825452	D91P	PreS1	G R	View
195	17825452	N91P	PreS1	G R	View
196	17825452	I91P	PreS1	G R	View
197	17825452	L91P	PreS1	G R	View
198	17825452	H51Y	PreS1	G R	View
199	17825452	T51Y	PreS1	G R	View
200	17825452	S51Y	PreS1	G R	View
201	17825452	P51Y	PreS1	G R	View
202	17825452	N51Y	PreS1	G R	View
203	17825452	D91A	PreS1	G R	View
204	17825452	N91A	PreS1	G R	View
205	17825452	I91A	PreS1	G R	View
206	17825452	L91A	PreS1	G R	View
207	17825452	S101V	PreS1	G R	View
208	17825452	Q104P	PreS1	G R	View
209	17825452	K104P	PreS1	G R	View
210	18939932	W4P	PreS1	R C	View
211	18939932	W4R	PreS1	R C	View
212	18939932	K7T	PreS1	R C	View
213	18939932	K7N	PreS1	R C	View
214	18939932	A81T	PreS1	R C	View
215	20419326	C2964A	PreS1	S C	View
216	20419326	C3116T	PreS1	S C	View
217	20419326	T3116C	PreS1	S C	View
218	21104161	C3060A	PreS1	S C	View
219	21104161	C3060T	PreS1	S C	View
220	21104161	C3116T	PreS1	S C	View
221	21108338	A2962G	PreS1	G C	View
222	21785721	2447_489 DEL1256	PreS1	S C	View
223	21785721	2846_2865 DEL18	PreS1	S C	View
224	21785721	3018_3202 DEL183	PreS1	S C	View
225	21785721	3024_3193 DEL168	PreS1	S C	View
226	23852705	F53L	PreS1	S C	View
227	23852705	T2857C	PreS1	S C	View
228	23852705	W4R	PreS1	S C	View
229	25333524	S98T	PreS1	S C	View
230	25333524	T3139A	PreS1	S C	View
231	25351410	C2990T	PreS1	R C	View
232	25351410	A90V	PreS1	R C	View
233	27651827	V49A	PreS1	S C	View
234	27651827	T52R	PreS1	S C	View
235	27651827	P25L	PreS1	S C	View
236	27651827	K85Q	PreS1	S C	View
237	27651827	P64S	PreS1	S C	View
238	27651827	N19T	PreS1	S C	View
239	27651827	S100V	PreS1	S C	View
240	27651827	R38G	PreS1	S C	View
241	27651827	P30Q	PreS1	S C	View
242	27651827	W42G	PreS1	S C	View
243	27651827	N14K	PreS1	S C	View
244	27727182	C3026W	PreS1	R C	View
245	27727182	A60V	PreS1	R C	View
246	27727182	A60E	PreS1	R C	View
247	28332361	D114E	PreS1	R C	View
248	28332361	N46H	PreS1	R C	View
249	28332361	T86A	PreS1	R C	View
250	28332361	W4R	PreS1	R C	View
251	28332361	P65S	PreS1	R C	View
252	28332361	F34L	PreS1	R C	View
253	28332361	L82H	PreS1	R C	View
254	28332361	G83S	PreS1	R C	View
255	28332361	H116R	PreS1	R C	View
256	28332361	I84T	PreS1	R C	View
257	31877352	T68I	PreS1	I C	View
258	33803998	I84T	PreS1	G S	View
259	33803998	I84M	PreS1	G S	View
260	33803998	I84L	PreS1	G S	View
261	33803998	I84V	PreS1	G S	View
262	33803998	A90T	PreS1	G S	View
263	33803998	A90V	PreS1	G S	View
264	17258721	T23G	PreS1	G	View
265	17258721	T126A	PreS1	G	View
266	17258721	T127A	PreS1	G	View
267	17258721	C193G	PreS1	G	View
268	17258721	G184T	PreS1	G	View
269	17258721	C158G	PreS1	G	View
270	17258721	G338A	PreS1	G	View
271	17258721	A166G	PreS1	G	View
272	17258721	A136G	PreS1	G	View
273	17258721	C157G	PreS1	G	View
274	17258721	A167T	PreS1	G	View
275	17258721	A167G	PreS1	G	View
276	17258721	T187G	PreS1	G	View
277	17503077	N48T	PreS1	C	View
278	17503077	Q82P	PreS1	C	View
279	17503077	R35K	PreS1	C	View
280	17503077	E54D	PreS1	C	View
281	17503077	H16Q	PreS1	C	View
282	17503077	K86T	PreS1	C	View
283	17503077	T19S	PreS1	C	View
284	17503077	S96F	PreS1	C	View
285	17503077	P94L	PreS1	C	View
286	17503077	W77T	PreS1	C	View
287	17503077	T53K	PreS1	C	View
288	17503077	H86A	PreS1	C	View
289	17503077	F67S	PreS1	C	View
290	17503077	S77W	PreS1	C	View
291	17503077	F67L	PreS1	C	View
292	17503077	D91N	PreS1	C	View
293	17503077	K86Q	PreS1	C	View
294	17503077	E54Q	PreS1	C	View
295	17503077	T97N	PreS1	C	View
296	17503077	P93Q	PreS1	C	View
297	17503077	S96A	PreS1	C	View
298	19570861	G2A	PreS1	R	View
299	21108338	T2857C	PreS1	C	View
300	21108338	C2875A	PreS1	C	View
301	21108338	C2875T	PreS1	C	View
302	21108338	G2946A	PreS1	C	View
303	21108338	G2946C	PreS1	C	View
304	21108338	C2964A	PreS1	C	View
305	21108338	C3026T	PreS1	C	View
306	21108338	A3054C	PreS1	C	View
307	21108338	A3054T	PreS1	C	View
308	21108338	C3060A	PreS1	C	View
309	21108338	C3060T	PreS1	C	View
310	21108338	C3063G	PreS1	C	View
311	21108338	T3066A	PreS1	C	View
312	21108338	T3066C	PreS1	C	View
313	21108338	A3120T	PreS1	C	View
314	21108338	A3120C	PreS1	C	View
315	21108338	A3120G	PreS1	C	View
316	21108338	G3191A	PreS1	C	View
317	21108338	G3191C	PreS1	C	View
318	23951004	A90V	PreS1	C	View
319	23951004	A90S	PreS1	C	View
320	24119014	C3050T	PreS1	C	View
321	24119014	T68I	PreS1	C	View
322	24119014	G3109A	PreS1	C	View
323	24119014	C3157A	PreS1	C	View
324	24119014	T2980C	PreS1	C	View
325	24119014	A2999G	PreS1	C	View
326	24119014	V88M	PreS1	C	View
327	24119014	Q104K	PreS1	C	View
328	24119014	F45L	PreS1	C	View
329	24119014	N51S	PreS1	C	View
330	24849936	C3026A	PreS1	C	View
331	24849936	C3026T	PreS1	C	View
332	25501679	A2962G	PreS1	C	View
333	25501679	C2964A	PreS1	C	View
334	27486882	G76A	PreS1	G	View
335	27486882	I273L	PreS1	G	View
336	27486882	L54P	PreS1	G	View
337	27486882	N222T	PreS1	G	View
338	27486882	P124K	PreS1	G	View
339	27486882	T40S	PreS1	G	View
340	30943997	A54Q	PreS1	G	View
341	30943997	L67F	PreS1	G	View
342	30943997	I74V	PreS1	G	View
343	30943997	T86A	PreS1	G	View
344	30943997	S89P	PreS1	G	View
345	30943997	T90A	PreS1	G	View
346	30943997	I91V	PreS1	G	View
347	32722114	2855-2872 DEL	PreS1	C	View
348	32840739	2971-3177 DEL	PreS1	C	View
349	32840739	42-110 DEL	PreS1	C	View
350	12050364	A119F	PreS1		View
351	19759159	C147S	PreS1		View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
Drugs mentioned in the relevant literature.

G
Genotypes/subtypes mentioned in the relevant literature.

R
Reference genomes mentioned in the relevant literature.

S
Viral sequences mentioned in the relevant literature.

C
Geographical distribution of the source mentioned in the relevant literature.

CI
Clinical information is available in the relevant literature.

I
This mutation is related to the immune escape.


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