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Mutation Information
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Mutation Site
|
A90V |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
PreS1 |
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Genotype/Subtype
|
C |
Literature Information
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PubMed PMID
|
33803998
|
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Published Year
|
2021 |
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Journal
|
Microorganisms |
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Title
|
rt269I Type of Hepatitis B Virus (HBV) Polymerase versus rt269L Is More Prone to Mutations within HBV Genome in Chronic Patients Infected with Genotype C2: Evidence from Analysis of Full HBV Genotype C2 Genome. |
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Author
|
Jeong H,Kim DH,Choi YM,Choi H,Kim D,Kim BJ |
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Evidence
|
We found a total of five types of signature NS mutations in the S ORF (I84T/M/L/V and A90T/V in PreS1, F141L in PreS2, and I68T and L213I/S in S). Of these, the frequency in all four types but one rt269L signature type (I68T in the S region) was significantly or tended to be higher in rt269I HBV strains than in rt269L.
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HBV Mutation Detail Information