|
Mutation Information
|
Mutation Site
|
A2964C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreS1 |
|
Genotype/Subtype
|
C |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
20419326
|
|
Disease
|
HBV infection;
Liver cirrhosis;
Hepatocellular carcinoma
|
|
Published Year
|
2010 |
|
Journal
|
Journal of gastroenterology |
|
Title
|
Significant association of different preS mutations with hepatitis B-related cirrhosis or hepatocellular carcinoma. |
|
Author
|
Yin J,Xie J,Zhang H,Shen Q,Han L,Lu W,Han Y,Li C,Ni W,Wang H,Cao G |
|
Evidence
|
Multivariate regression analyses showed that C2964A, C3116T, and C7A were novel factors associated with HCC compared with those without HCC, whereas A2964C and T3116C were independently associated with cirrhosis compared with ASCs and the CHB patients.
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HBV Mutation Detail Information