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Mutation Information
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Mutation Site
|
I74V |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PreS1 |
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Genotype/Subtype
|
A |
Literature Information
|
PubMed PMID
|
30943997
|
|
Disease
|
HBV infection
|
|
Published Year
|
2019 |
|
Journal
|
Virology journal |
|
Title
|
Molecular and serological characterization of hepatitis B vaccine breakthrough infections in serial samples from two plasma donors. |
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Author
|
Kuhns MC,McNamara AL,Holzmayer V,Cloherty GA |
|
Evidence
|
Results for 6272 revealed the presence of multiple substitutions in preS-S and in the reverse transcriptase (RT) region overlapping the envelope. PreS1 (aa 1–119) substitutions were: A54Q, L67F, I74V, T86A, S89P, T90A, I91V.
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HBV Mutation Detail Information