|
Mutation Information
|
Mutation Site
|
A90T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreS1 |
|
Genotype/Subtype
|
C |
Literature Information
|
PubMed PMID
|
33803998
|
|
Published Year
|
2021 |
|
Journal
|
Microorganisms |
|
Title
|
rt269I Type of Hepatitis B Virus (HBV) Polymerase versus rt269L Is More Prone to Mutations within HBV Genome in Chronic Patients Infected with Genotype C2: Evidence from Analysis of Full HBV Genotype C2 Genome. |
|
Author
|
Jeong H,Kim DH,Choi YM,Choi H,Kim D,Kim BJ |
|
Evidence
|
We found a total of five types of signature NS mutations in the S ORF (I84T/M/L/V and A90T/V in PreS1, F141L in PreS2, and I68T and L213I/S in S). Of these, the frequency in all four types but one rt269L signature type (I68T in the S region) was significantly or tended to be higher in rt269I HBV strains than in rt269L.
|
|
|
HBV Mutation Detail Information