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Mutation Information
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Mutation Site
|
C147S |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
PreS1 |
Literature Information
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PubMed PMID
|
19759159
|
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Published Year
|
2009 |
|
Journal
|
Journal of virology |
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Title
|
The pre-S1 and antigenic loop infectivity determinants of the hepatitis B virus envelope proteins are functionally independent. |
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Author
|
Le Duff Y,Blanchet M,Sureau C |
|
Evidence
|
Finally, we showed that C147S, an AGL infectivity-deficient substitution, exerted a dominant-negative effect on infectivity, likely reflecting an involvement of C147 in intermolecular disulfide bonds.
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HBV Mutation Detail Information