Literature Information
PubMed PMID
|
31776247
|
Published year
|
2019 |
Journal
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Proceedings of the National Academy of Sciences of the United States of America |
Title
|
Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors. |
Author
|
Patro SC,Brandt LD,Bale MJ,Halvas EK,Joseph KW,Shao W,Wu X,Guo S,Murrell B,Wiegand A,Spindler J,Raley C,Hautman C,Sobolewski M,Fennessey CM,Hu WS,Luke B,Hasson JM,Niyongabo A,Capoferri AA,Keele BF,Milush J,Hoh R,Deeks SG,Maldarelli F,Hughes SH,Coffin JM,Rausch JW,Mellors JW,Kearney MF |
Evidence
|
Integration sites were obtained for 4 MDA-amplified proviruses in the ACH-2 cells. All were on chromosome 7 at the same position within the NT5C3A gene, identical to the major reported integration site in ACH-2 cells
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