XMRV VIS-Cistrome Factor Overlap in each human chromosome

This page provides a heatmap of three VIS-Factors overlap counts by chromosome to help users have a better understanding of the distribution of VIS-Factors overlap in the human genome.


XMRV Overall Heatmap
CA: chromatin accessibility TFBS: transcription factor binding site HM: histone modification
Browse data distribution by Chromosome or Factor
*Please select the Chromosome or Factor you are interested in, the page will be automatically redirected.
 
 
VIS locations with VIS-cistrome overlap information and VIS details for each chromosome

Rank of Overlapped Records (S) DVID Location HM (S) TFBS (S) CA (S) Sum (S) HM (B) TFBS (B) CA (B) Sum (B) Case/Length Detail
1 8100028 41362140, 41368107 1180 118 18 1316 2407 616 127 3150
Case 2
|
5967
View
2 8100003 26863521, 26864307 505 80 1 586 1313 203 19 1535
Case 2
|
786
View
3 8100001 8861088, 8878688 55 43 6 104 3008 3673 1779 8460
Case 2
|
17600
View
4 8100020 909993, 962718 68 8 1 77 6079 4367 1478 11924
Case 2
|
52725
View
5 8100009 174370990, 174394146 10 10 567 469 161 1197
Case 2
|
23156
View
Contents
Description
VIS-Cistrome factor overlapping Description

The overlaps between integration site and cistrome are retrieved by genome search engine GIGGLE (Ryan M Layer et al. 2018). We built three indexs including histone modification, transcription factor binding site and chromatin accessibility, then we searched the significance of shared genomic loci (overlaps) between query VIS and Cistrome (Rongbin Zheng et al. 2019) genome interval files. So one VIS may have several overlaps with multiple Cistrome factor-related samples, the associated factor and overlap amount could indicate that the virus integration site is a potentially functional DNA element.


  • XMRV Overall Heatmap

This heatmap is an overall statistics for XMRV VIS-Cistrome factor overlapped records by chromosome. The darker the red, the greater the overlapped records number. The user can view specific number by moving mouse pointer.

  • Browse data by Chromosome or Factor

The user can browse XMRV VIS-Cistrome factor overlapped records data by specific chromosome or statistics histogram for specific Cistrome factor when users click the chromosome or Cistrome factor the user are interested in.

  • VIS locations with VIS-cistrome overlap information and VIS details for each chromosome

This table showed the VIS locations with VIS-cistrome overlap information and VIS details for each chromosome, you can click green button with number which indicates the overlapped records of this VIS and 3 cistrome factor (histone modification, transcription factor binding site and chromatin accessibility) to inspect details of cistrome sample and factor information, you can click "Detail" button to inspect other information of this VIS.

Case 1
: The deletion of human fragments during the integration event.
Case 2
: Due to the experimental method/design, two viral insertion positions were provided in the literature.
Length:
~40 bp
41 bp~1000 bp
1001 bp~