MCV VIS Detail Information

> This page shows VIS [7000020] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 7000020
VISID TVIS43000055
Chromosome chr11
GRCh38 Location 25063435
Disease Merkel cell carcinoma  
Sample Cell line
Virus Reference Genome EU375803
Target Gene LUZP2     
Literature Information
PubMed PMID 30873613
Published year 2019
Journal International journal of cancer
Title Characterization of six Merkel cell polyomavirus-positive Merkel cell carcinoma cell lines: Integration pattern suggest that large T antigen truncating events occur before or during integration.
Author Schrama D,Sarosi EM,Adam C,Ritter C,Kaemmerer U,Klopocki E,König EM,Utikal J,Becker JC,Houben R
Evidence The LT-truncating stop codon mutations and integration sites were affirmed in the respective clinical patient samples. Inverse PCR suggested that three of the cell lines contained MCPyV genomes as concatemers. This notion was confirmed for the two cell lines with known integration sites.

Contents
Description
  • Site Information
Detail information of site [7000020]
  • Literature Information
The details of literature that this site is associated with.