MCV VIS Detail Information

> This page shows VIS [7000010] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.

Site Information

Literature Information

PubMed PMID	28049147
Published year	2017
Journal	mBio
Title	Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma.
Author	Starrett GJ,Marcelus C,Cantalupo PG,Katz JP,Cheng J,Akagi K,Thakuria M,Rabinowits G,Wang LC,Symer DE,Pipas JM,Harris RS,DeCaprio JA
Evidence	One chimeric junction was mapped at chr20:32132694 within CBFA2T2. Another chimeric junction was mapped between exon 1 of CBFA2T2 and the large T antigen splice acceptor at position 861 in MCPyV. One chimeric junction was mapped within an intron of FLJ46066 (approximately at chr3:182180601), indicating a chimeric transcript antisense to the FLJ46066 gene. The other three chimeric junctions mapped within the ECH1 (at host positions chr19:39307703 and chr19:39307378).Of the two tumors for which we also had whole-genome sequencing (WGS) data, sample-088 contained a single chimeric junction within two overlapping genes, RP3-348I23.2 and CDKAL1 (at chr6:20757000).