MCV VIS Detail Information

> This page shows VIS [7000002] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 7000002
VISID TVIS43000038
Chromosome chr3
GRCh38 Location 61561985
Disease Merkel cell carcinoma  
Sample Tumor
Virus Reference Genome EU375803
Target Gene PTPRG     
Literature Information
PubMed PMID 18202256
Published year 2008
Journal Science (New York, N.Y.)
Title Clonal integration of a polyomavirus in human Merkel cell carcinoma.
Author Feng H,Shuda M,Chang Y,Moore PS
Evidence In six of eight MCV-positive MCCs, viral DNA was integrated within the tumor genome in a clonal pattern, suggesting that MCV infection and integration preceded clonal expansion of the tumor cells. Thus, MCV may be a contributing factor in the pathogenesis of MCC.

Contents
Description
  • Site Information
Detail information of site [7000002]
  • Literature Information
The details of literature that this site is associated with.