HTLV1 VIS Detail Information

> This page shows VIS [6400015] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.

Site Information

DVID	6400015
Chromosome	chr1
GRCh38 Location	178255910, 178255965
Disease	Adult T cell leukemia/lymphoma
Sample	tumor

Literature Information

PubMed PMID	31618639
Published year	2019
Journal	Cell reports
Title	The Nature of the HTLV-1 Provirus in Naturally Infected Individuals Analyzed by the Viral DNA-Capture-Seq Approach.
Author	Katsuya H,Islam S,Tan BJY,Ito J,Miyazato P,Matsuo M,Inada Y,Iwase SC,Uchiyama Y,Hata H,Sato T,Yagishita N,Araya N,Ueno T,Nosaka K,Tokunaga M,Yamagishi M,Watanabe T,Uchimaru K,Fujisawa JI,Utsunomiya A,Yamano Y,Satou Y
Evidence	The retrovirus human T-cell leukemia virus type 1 (HTLV-1) integrates into the host DNA, achieves persistent infection, and induces human diseases. Here, we demonstrate that viral DNA-capture sequencing (DNA-capture-seq) is useful to characterize HTLV-1 proviruses in naturally virus-infected individuals, providing comprehensive information about the proviral structure and the viral integration site.