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HPV VIS Detail Information

> This page shows VIS [5405000] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 5405000
Chromosome chr19
GRCh38 Location 55650097
Disease Cervical carcinoma  
Sample Tumor
Target Gene CCDC106     
Literature Information
PubMed PMID 33023834
Published year 2020
Journal Journal of genetics and genomics = Yi chuan xue bao
Title HPV-CCDC106 integration alters local chromosome architecture and hijacks an enhancer by three-dimensional genome structure remodeling in cervical cancer.
Author Cao C,Hong P,Huang X,Lin D,Cao G,Wang L,Feng B,Wu P,Shen H,Xu Q,Ren C,Meng Y,Zhi W,Yu R,Wei J,Ding W,Tian X,Zhang Q,Li W,Gao Q,Chen G,Li K,Sung WK,Hu Z,Wang H,Li G,Wu P
Evidence In summary, we found that HPV-CCDC106 integration altered local chromosome architecture and hijacked an enhancer via 3D genome structure remodeling. Thus, this study provides insight into the 3D structural mechanism underlying HPV integration in cervical carcinogenesis.
Contents
Description
  • Site Information
Detail information of site [5405000]
  • Literature Information
The details of literature that this site is associated with.