DVID
|
5403552 |
Chromosome
|
chr1 |
GRCh38 Location
|
175958230 |
Disease
|
Cervical carcinoma |
Sample
|
Tumor |
Target Gene
|
COP1 |
Literature Information
PubMed PMID
|
33023834
|
Published year
|
2020 |
Journal
|
Journal of genetics and genomics = Yi chuan xue bao |
Title
|
HPV-CCDC106 integration alters local chromosome architecture and hijacks an enhancer by three-dimensional genome structure remodeling in cervical cancer. |
Author
|
Cao C,Hong P,Huang X,Lin D,Cao G,Wang L,Feng B,Wu P,Shen H,Xu Q,Ren C,Meng Y,Zhi W,Yu R,Wei J,Ding W,Tian X,Zhang Q,Li W,Gao Q,Chen G,Li K,Sung WK,Hu Z,Wang H,Li G,Wu P |
Evidence
|
In summary, we found that HPV-CCDC106 integration altered local chromosome architecture and hijacked an enhancer via 3D genome structure remodeling. Thus, this study provides insight into the 3D structural mechanism underlying HPV integration in cervical carcinogenesis.
|
|
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