HPV VIS Detail Information

> This page shows VIS [5403329] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.

Site Information

Literature Information

PubMed PMID	33023834
Published year	2020
Journal	Journal of genetics and genomics = Yi chuan xue bao
Title	HPV-CCDC106 integration alters local chromosome architecture and hijacks an enhancer by three-dimensional genome structure remodeling in cervical cancer.
Author	Cao C,Hong P,Huang X,Lin D,Cao G,Wang L,Feng B,Wu P,Shen H,Xu Q,Ren C,Meng Y,Zhi W,Yu R,Wei J,Ding W,Tian X,Zhang Q,Li W,Gao Q,Chen G,Li K,Sung WK,Hu Z,Wang H,Li G,Wu P
Evidence	In summary, we found that HPV-CCDC106 integration altered local chromosome architecture and hijacked an enhancer via 3D genome structure remodeling. Thus, this study provides insight into the 3D structural mechanism underlying HPV integration in cervical carcinogenesis.