Literature Information
PubMed PMID
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30016933
|
Published year
|
2018 |
Journal
|
BMC bioinformatics |
Title
|
HGT-ID: an efficient and sensitive workflow to detect human-viral insertion sites using next-generation sequencing data. |
Author
|
Baheti S,Tang X,O'Brien DR,Chia N,Roberts LR,Nelson H,Boughey JC,Wang L,Goetz MP,Kocher JA,Kalari KR |
Evidence
|
We applied HGT-ID to The Cancer Genome Atlas (TCGA) whole-genome sequencing data (WGS) from liver tumor-normal pairs. Multiple hepatitis B virus (HBV) integration sites were identified in TCGA liver samples and confirmed by HGT-ID using the RNA-Seq data from the matched liver pairs.
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