Literature Information
PubMed PMID
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30264502
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Published year
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2018 |
Journal
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Genes, chromosomes & cancer |
Title
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Nuclear factor I X is a recurrent target for HPV16 insertions in anal carcinomas. |
Author
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Jeannot E,Harlé A,Holmes A,Sastre-Garau X |
Evidence
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Other genes targeted by integration were IL20RB, RPS6KA2, MSRA1, PIP5K1B, SLX4IP, CECR1, BCAR3, ATF6, CSNK1G1, APBA2, AGK, ILF3, PVT1, TRMT1, RAD51B, FASN, CCDC57, DSG3, and ZNF563. We identified recurrent targeting of NFIX by HPV16 insertion in anal carcinomas, supporting a role for this gene in oncogenesis, as reported for non-HPV tumors.
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