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HPV VIS Detail Information

> This page shows VIS [5402850] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 5402850
Chromosome chr19
GRCh38 Location 13016553, 13105062
Disease Squamous-cell carcinoma  
Sample Tumor
Target Gene TRMT1   NFIX     
Literature Information
PubMed PMID 30264502
Published year 2018
Journal Genes, chromosomes & cancer
Title Nuclear factor I X is a recurrent target for HPV16 insertions in anal carcinomas.
Author Jeannot E,Harlé A,Holmes A,Sastre-Garau X
Evidence Other genes targeted by integration were IL20RB, RPS6KA2, MSRA1, PIP5K1B, SLX4IP, CECR1, BCAR3, ATF6, CSNK1G1, APBA2, AGK, ILF3, PVT1, TRMT1, RAD51B, FASN, CCDC57, DSG3, and ZNF563. We identified recurrent targeting of NFIX by HPV16 insertion in anal carcinomas, supporting a role for this gene in oncogenesis, as reported for non-HPV tumors.
Contents
Description
  • Site Information
Detail information of site [5402850]
  • Literature Information
The details of literature that this site is associated with.