Literature Information
PubMed PMID
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29487700
|
Published year
|
2018 |
Journal
|
Oncotarget |
Title
|
Increased high mobility group A 2 expression promotes transition of cervical intraepithelial neoplasm into cervical cancer. |
Author
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Wang L,Shen H,Zhu D,Feng B,Yu L,Tian X,Ren C,Gao C,Li X,Ma D,Hu Z,Wang H |
Evidence
|
HPV integration sites were analyzed in 40 cervical cancer samples, while copy number variation and protein expression were assessed in 19 normal cervixes, 49 cervical intraepithelial neoplasia (CIN), and 52 cervical cancer samples. Overall, 25 HR-HPV integrating loci were detected in 24 cervical samples; HMGA2 was the only recurring integration site.
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