|
DVID
|
5402674 |
|
Chromosome
|
chr3 |
|
GRCh38 Location
|
190138396 |
|
Disease
|
Cervical carcinoma |
|
Sample
|
tumor |
|
Target Gene
|
P3H2 |
Literature Information
|
PubMed PMID
|
32025001
|
|
Published year
|
2020 |
|
Journal
|
Nature genetics |
|
Title
|
The landscape of viral associations in human cancers. |
|
Author
|
Zapatka M,Borozan I,Brewer DS,Iskar M,Grundhoff A,Alawi M,Desai N,Sültmann H,Moch H,PCAWG Pathogens.,Cooper CS,Eils R,Ferretti V,Lichter P,PCAWG Consortium. |
|
Evidence
|
For HBV, HPV16, HPV18 and adeno-associated virus-2 (AAV2), viral integration was associated with local variations in genomic copy numbers. Integrations at the TERT promoter were associated with high telomerase expression evidently activating this tumor-driving process. High levels of endogenous retrovirus (ERV1) expression were linked to a worse survival outcome in patients with kidney cancer.
|
|
|
HPV VIS Detail Information