HPV VIS Detail Information

> This page shows VIS [5402511] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 5402511
Chromosome chr10
GRCh38 Location 49916148
Disease Cervical intraepithelial neoplasia  
Sample tumor
Literature Information
PubMed PMID 31102403
Published year 2019
Journal Carcinogenesis
Title Risk stratification of cervical lesions using capture sequencing and machine learning method based on HPV and human integrated genomic profiles.
Author Tian R,Cui Z,He D,Tian X,Gao Q,Ma X,Yang JR,Wu J,Das BC,Severinov K,Hitzeroth II,Debata PR,Xu W,Zhong H,Fan W,Chen Y,Jin Z,Cao C,Yu M,Xie W,Huang Z,Bao Y,Xie H,Yao S,Hu Z
Evidence Generally, HPV integration events (11 in HPV+, 25 in CIN1 and 56 in CIN2+), non-synonymous mutations (2 in CIN1, 12 in CIN2+) and copy number variations (19.1 in HPV+, 29.4 in CIN1 and 127 in CIN2+) increased from HPV+ to CIN2+. Interestingly, 'common' deletion of mitochondrial chromosome was significantly observed in CIN2+ (P = 0.009).

Contents
Description
  • Site Information
Detail information of site [5402511]
  • Literature Information
The details of literature that this site is associated with.