HPV VIS Detail Information

> This page shows VIS [5401395] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 5401395
Chromosome chr1
GRCh38 Location 190108603
Disease Cervical carcinoma  
Sample tumor
Target Gene BRINP3     
Literature Information
PubMed PMID 30567904
Published year 2019
Journal Journal of medical genetics
Title Comprehensive genomic variation profiling of cervical intraepithelial neoplasia and cervical cancer identifies potential targets for cervical cancer early warning.
Author Huang J,Qian Z,Gong Y,Wang Y,Guan Y,Han Y,Yi X,Huang W,Ji L,Xu J,Su M,Yuan Q,Cui S,Zhang J,Bao C,Liu W,Chen X,Zhang M,Gao X,Wu R,Zhang Y,Xu H,Zhu S,Zhu H,Yang L,Xu X,Zhou P,Liang Z
Evidence In addition, HPV integration breakpoints occurred in 97.8% of the CC samples, 70.5% of the CIN samples and 42.8% of the normal cervical samples with HPV infection. Integrations of high-risk HPV strains in CCs, including HPV16, 18, 33 and 58, also occurred in the CIN samples. Moreover, gene mutations were detected in 52% of the CIN specimens, and 54.8% of these mutations occurred in genes that also mutated in CCs.

Contents
Description
  • Site Information
Detail information of site [5401395]
  • Literature Information
The details of literature that this site is associated with.