HPV VIS Detail Information

> This page shows VIS [5300332] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 5300332
Chromosome chr7
GRCh38 Location 150336065
Disease Cervical carcinoma  
Target Gene LRCC61     
Literature Information
PubMed PMID 33191407
Published year 2021
Journal British journal of cancer
Title Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site.
Author Kamal M,Lameiras S,Deloger M,Morel A,Vacher S,Lecerf C,Dupain C,Jeannot E,Girard E,Baulande S,Dubot C,Kenter G,Jordanova ES,Berns EMJJ,Bataillon G,Popovic M,Rouzier R,Cacheux W,Le Tourneau C,Nicolas A,Servant N,Scholl SM,Bièche I,RAIDs Consortium.
Evidence This is to our knowledge the first study assessing the prognostic value of HPV integration in a prospectively annotated CC cohort, which detects a hotspot of HPV integration at MACROD2; involved in impaired PARP1 activity and chromosome instability.

Contents
Description
  • Site Information
Detail information of site [5300332]
  • Literature Information
The details of literature that this site is associated with.