HPV VIS Detail Information

> This page shows VIS [5300122] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.

Site Information

Literature Information

PubMed PMID	33191407
Published year	2021
Journal	British journal of cancer
Title	Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site.
Author	Kamal M,Lameiras S,Deloger M,Morel A,Vacher S,Lecerf C,Dupain C,Jeannot E,Girard E,Baulande S,Dubot C,Kenter G,Jordanova ES,Berns EMJJ,Bataillon G,Popovic M,Rouzier R,Cacheux W,Le Tourneau C,Nicolas A,Servant N,Scholl SM,Bièche I,RAIDs Consortium.
Evidence	This is to our knowledge the first study assessing the prognostic value of HPV integration in a prospectively annotated CC cohort, which detects a hotspot of HPV integration at MACROD2; involved in impaired PARP1 activity and chromosome instability.