HPV VIS Detail Information

> This page shows VIS [5202015] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.

Site Information

Literature Information

PubMed PMID	32714374
Published year	2020
Journal	Frontiers in genetics
Title	Accurate Detection of HPV Integration Sites in Cervical Cancer Samples Using the Nanopore MinION Sequencer Without Error Correction.
Author	Yang W,Liu Y,Dong R,Liu J,Lang J,Yang J,Wang W,Li J,Meng B,Tian G
Evidence	Among the top five most abundant breakpoints, There were 3 located in chromosome 20, HPV16:2804,chr20:32516985 (406 reads), HPV16:7139,chr20:32478733 (169 reads), HPV16:4276,chr20:32502143(51 reads), and two were in chrX, HPV16:5534,chrX:20464412 (132 reads), HPV16:3163,chrX: 20462930 (50 reads). Figure 3B indicates the integration site distribution in the HPV genome. Within the 60 identified integration sites, 18 were in the L2 gene, 12 in L1, 11 in E1, 7 in E2, and <4 in the each of the other genes (E6, LCR, E5, and E7).