Literature Information
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PubMed PMID
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30872350
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Published year
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2019 |
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Journal
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Genome research |
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Title
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A virome-wide clonal integration analysis platform for discovering cancer viral etiology. |
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Author
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Chen X,Kost J,Sulovari A,Wong N,Liang WS,Cao J,Li D |
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Evidence
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By applying this platform to cancer WGS data sets with proven or speculated viral etiology, we newly identified or confirmed clonal integrations of hepatitis B virus (HBV), human papillomavirus (HPV), Epstein-Barr virus (EBV), and BK Virus (BKV), suggesting the involvement of these viruses in early stages of tumorigenesis in affected tumors, such as HBV in TERT and KMT2B (also known as MLL4) gene loci in liver cancer, HPV and BKV in bladder cancer, and EBV in non-Hodgkin's lymphoma.
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HPV VIS Detail Information