HPV VIS Detail Information

> This page shows VIS [5002120] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 5002120
VISID TVIS20004217
Chromosome chr2
GRCh38 Location 27137265
Disease Cervical carcinoma  
Sample Cell line
Virus Reference Genome Not given
Target Gene PRR30     
Literature Information
PubMed PMID 30679491
Published year 2019
Journal Scientific reports
Title TaME-seq: An efficient sequencing approach for characterisation of HPV genomic variability and chromosomal integration.
Author Lagström S,Umu SU,Lepistö M,Ellonen P,Meisal R,Christiansen IK,Ambur OH,Rounge TB
Evidence HPV genomic variability and chromosomal integration are important in the HPV-induced carcinogenic process. TaME-seq combines tagmentation and multiplex PCR enrichment for simultaneous analysis of HPV variation and chromosomal integration, and it can also be adapted to other viruses. Chromosomal integration breakpoints and large deletions were identified in HPV positive cell lines and in one clinical sample. Efficient identification of both HPV variability and integration sites will be important for the study of HPV evolution and adaptability and may be an important tool for use in cervical cancer diagnostics.

Contents
Description
  • Site Information
Detail information of site [5002120]
  • Literature Information
The details of literature that this site is associated with.