DVID
|
4300026 |
Chromosome
|
chr7 |
GRCh38 Location
|
44919647 |
Disease
|
|
Target Gene
|
PURB |
Literature Information
PubMed PMID
|
33318172
|
Published year
|
2020 |
Journal
|
Proceedings of the National Academy of Sciences of the United States of America |
Title
|
HIV proviral DNA integration can drive T cell growth ex vivo. |
Author
|
Yoon JK,Holloway JR,Wells DW,Kaku M,Jetton D,Brown R,Coffin JM |
Evidence
|
Thus, HIV integration patterns linked to selective T cell outgrowth can be reproduced in cell culture. The single report of an HIV provirus in a case of AIDS-associated B-cell lymphoma with an HIV provirus in the same part of STAT3 also has implications for HIV-induced malignancy.
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