EBV VIS Detail Information

> This page shows VIS [3200021] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.

Site Information

DVID	3200021
Chromosome	chr17
GRCh38 Location	4945705, 4948705
Disease	Gastric carcinoma Nasopharyngeal carcinoma B-cell lymphoma
Target Gene	PFN1

Literature Information

PubMed PMID	31481499
Published year	2019
Journal	Cancer research
Title	Integrated Pan-Cancer Map of EBV-Associated Neoplasms Reveals Functional Host-Virus Interactions.
Author	Chakravorty S,Yan B,Wang C,Wang L,Quaid JT,Lin CF,Briggs SD,Majumder J,Canaria DA,Chauss D,Chopra G,Olson MR,Zhao B,Afzali B,Kazemian M
Evidence	We used these chimeric reads to determine the frequency and location of EBV integration into the human genome across different cancers ,We annotated these 56 specific integration loci with their nearest genes and analyzed their functional properties. These include integration at B2M, CD74, and HLA-C loci, which are part of the major histocompatibility class I and II complexes.