EBV VIS Detail Information

> This page shows VIS [3000417] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.

Site Information

DVID	3000417
VISID	TVIS42000942
Chromosome	chr2
GRCh38 Location	219109048, 219109065
Disease	Extranodal natural killer T-cell lymphoma
Sample	Tumor
Virus Reference Genome	NC007605
Target Gene	NHEJ1

Literature Information

PubMed PMID	30546078
Published year	2019
Journal	Leukemia
Title	Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma.
Author	Peng RJ,Han BW,Cai QQ,Zuo XY,Xia T,Chen JR,Feng LN,Lim JQ,Chen SW,Zeng MS,Guo YM,Li B,Xia XJ,Xia Y,Laurensia Y,Chia BKH,Huang HQ,Young KH,Lim ST,Ong CK,Zeng YX,Bei JX
Evidence	We also identified frequent focal EBV genome deletions and integrated EBV fragments in the host genome. Furthermore, we observed transcriptional defects of the BARTs miRNA by deletion, and the disruption of host NHEJ1 by integrated EBV fragment, implying novel pathogenic mechanisms of EBV.