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AAV2 VIS Detail Information

> This page shows VIS [2000006] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 2000006
VISID TVIS10017433
Chromosome chr4
GRCh38 Location 121822680, 121822689
Disease Hepatocellular carcinoma  
Sample Tumor
Virus Reference Genome AF043303.1
Target Gene CCNA2     
Literature Information
PubMed PMID 30531861
Published year 2018 Dec 7
Journal Nature communications
Title Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress.
Author Bayard Q, Meunier L, Peneau C, Renault V, Shinde J, Nault JC,et.al
Evidence We also identified one tumor with HBV insertion and 3 tumors with AAV2 insertions in CCNA2. Finally, 6 tumors strongly overexpressed CCNA2 (FPKM > 15), 3 of which displayed 23–48 Mb intra-chromosomal deletions linking the intergenic region downstream CCNA2 with the highly expressed ALB, AFP, and ADH6 genes
Contents
Description
  • Site Information
Detail information of site [2000006]
  • Literature Information
The details of literature that this site is associated with.