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HBV VIS Detail Information

> This page shows VIS [1404527] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 1404527
Chromosome chr7
GRCh38 Location 101111775
Disease   
Sample HepG2.2.16 cell lines
Target Gene SERPINE1     
Literature Information
PubMed PMID 32100258
Published year 2020
Journal Hepatology international
Title Noninvasive chimeric DNA profiling identifies tumor-originated HBV integrants contributing to viral antigen expression in liver cancer.
Author Chen W,Zhang K,Dong P,Fanning G,Tao C,Zhang H,Guo S,Wang Z,Hong Y,Yang X,Lai S,Ding H,Zhao H,Zeng C,Protzer U,Zhang D
Evidence We achieve the efficient enrichment of plasma cell-free chimeric DNA from integration site, and demonstrate that chimeric DNA profiling in plasma is a promising noninvasive approach to monitor HBV integration in liver cancer development and to determine the ability of integrated sequences to express viral proteins that can be targeted, e.g. by immunotherapies.
Contents
Description
  • Site Information
Detail information of site [1404527]
  • Literature Information
The details of literature that this site is associated with.