Literature Information
PubMed PMID
|
31231470
|
Published year
|
2019 |
Journal
|
Oncotarget |
Title
|
Free episomal and integrated HBV DNA in HBsAg-negative patients with intrahepatic cholangiocarcinoma. |
Author
|
Pollicino T,Musolino C,Saitta C,Tripodi G,Lanza M,Raffa G,Tocco FCD,Raggi C,Bragazzi MC,Barbera A,Navarra G,Invernizzi P,Alvaro D,Raimondo G |
Evidence
|
Occult HBV infection is highly prevalent in patients with ICC. Both free viral genomes and integrated HBV DNA can be present in these cases. These results suggest an involvement of HBV in the carcinogenic process leading to ICC development even in cases with occult infection.
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