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HBV VIS Detail Information

> This page shows VIS [1400179] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 1400179
Chromosome chr1
GRCh38 Location 91810940
Disease Hepatocellular carcinoma  
Sample liver tissue
Target Gene TGFBR3     
Literature Information
PubMed PMID 32592629
Published year 2020
Journal Journal of viral hepatitis
Title Deep sequencing of liver explant transcriptomes reveals extensive expression from integrated hepatitis B virus DNA.
Author Ringlander J,Skoglund C,Prakash K,Andersson ME,Larsson SB,Tang KW,Rydell GE,Abrahamsson S,Castedal M,Norder H,Hellstrand K,Lindh M
Evidence Hence, HBV transcripts from integrated HBV DNA rather than from covalently closed circular HBV DNA (cccDNA) predominated in late-stage HBV infection, in particular in cases with hepatitis D virus co-infection. The findings support the suggestion that integrated HBV DNA can be a significant source of HBsAg in humans.
Contents
Description
  • Site Information
Detail information of site [1400179]
  • Literature Information
The details of literature that this site is associated with.