DVID
|
1100045 |
Chromosome
|
chr10 |
GRCh38 Location
|
87153862, 87154156 |
Disease
|
Hepatocellular carcinoma |
Sample
|
Cell line |
Virus Reference Genome
|
X72702 |
Literature Information
PubMed PMID
|
31064734
|
Published year
|
2019 |
Journal
|
Cancer genetics |
Title
|
Retrotransposon elements among initial sites of hepatitis B virus integration into human genome in the HepG2-NTCP cell infection model. |
Author
|
Chauhan R,Shimizu Y,Watashi K,Wakita T,Fukasawa M,Michalak TI |
Evidence
|
At one-hour p.i., HBV integration with retrotransposon THE-1B-LTR was identified, while virus insertions into proline-rich protein and protein kinase cGMP-dependent type 1 encoding genes were found at 3 h p.i. Fusion with runt-related transcription factor 1 was detected at 24 h p.i. and merges with 9 different genes at 13 day p.i.
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