HBV VIS Detail Information

> This page shows VIS [1100024] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.

Site Information

DVID	1100024
Chromosome	chr8
GRCh38 Location	117545320
Disease	Occult HBV infection Hepatocellular carcinoma
Sample	Cell line
Virus Reference Genome	FJ899779.1

Literature Information

PubMed PMID	31200735
Published year	2019
Journal	Journal of experimental & clinical cancer research : CR
Title	Viral integration drives multifocal HCC during the occult HBV infection.
Author	Chen XP,Long X,Jia WL,Wu HJ,Zhao J,Liang HF,Laurence A,Zhu J,Dong D,Chen Y,Lin L,Xia YD,Li WY,Li GB,Zhao ZK,Wu K,Hou Y,Yu JJ,Xiao W,Wang GP,Zhu PC,Chen W,Bai MZ,Jian YX,Kristiansen K,Chen Q
Evidence	Through analyzing the HBV integration sites in multifocal HCC, our data suggested that the tumor cells were monoclonal in origin and formed in the absence of active viral replication, whereas the affected host genes may subsequently contribute to carcinogenesis.