Literature Information
PubMed PMID
|
25636086
|
Published year
|
2015 |
Journal
|
Nature communications |
Title
|
Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. |
Author
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Fujimoto A,Furuta M,Shiraishi Y,Gotoh K,Kawakami Y,Arihiro K,Nakamura T,Ueno M,Ariizumi S,Nguyen HH,Shigemizu D,Abe T,Boroevich KA,Nakano K,Sasaki A,Kitada R,Maejima K,Yamamoto Y,Tanaka H,Shibuya T,Shibata T,Ojima H,Shimada K,Hayami S,Shigekawa Y,Aikata H,Ohdan H,Marubashi S,Yamada T,Kubo M,Hirano S,Ishikawa O,Yamamoto M,Yamaue H,Chayama K,Miyano S,Tsunoda T,Nakagawa H |
Evidence
|
HBV integration sites were identified in three LCBs (RK069:cHCC/CC, RK166:cHCC/CC, RK208:ICC) using read-pair information, indicating that HBV-infection and its genomic integration can be involved with the carcinogenesis of LCBs
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