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HBV VIS Detail Information

> This page shows VIS [1017598] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 1017598
VISID TVIS10017445
Chromosome chr16
GRCh38 Location 51319900, 51320015
Disease Hepatocellular carcinoma  
Sample Tumor
Virus Reference Genome Not given
Literature Information
PubMed PMID 26397742
Published year 2015
Journal Molecular medicine reports
Title Significance of the quantitative measurement of the chr16: 51320015 integration site in hepatocytes of patients with chronic hepatitis B.
Author Ruan P,Dai X,Sun Z,Zhou C,Yang F
Evidence The present study reported the presence of a hepatitis B virus (HBV) major integration site (MIS) chr16: 51320015 and discussed the significance of quantitative measurement of this site. Conventional reverse transcriptionquantitative polymerase chain reaction (RTqPCR) and Sanger sequencing were designed to verify the chr16: 51320015 integration site, and the copy numbers of this site were measured using molecular clone and SYBR Green I RTqPCR. In conclusion, the chr16:51320015 integration site may be a novel site, which persists in a several patients with HBV infection, and may accumulate in the hepatocytes due to clonal expansion.
Contents
Description
  • Site Information
Detail information of site [1017598]
  • Literature Information
The details of literature that this site is associated with.