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HBV VIS Detail Information

> This page shows VIS [1005737] detail information, including site information (chromosome, GRCh38 location, disease, sample, etc) and literature information.


Site Information
DVID 1005737
VISID TVIS10017441
Chromosome chr4
GRCh38 Location 121821600, 121821637
Disease Hepatocellular carcinoma  
Sample Tumor
Virus Reference Genome X02763
Target Gene CCNA2     
Literature Information
PubMed PMID 30531861
Published year 2018
Journal Nature communications
Title Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress.
Author Bayard Q,Meunier L,Peneau C,Renault V,Shinde J,Nault JC,Mami I,Couchy G,Amaddeo G,Tubacher E,Bacq D,Meyer V,La Bella T,Debaillon-Vesque A,Bioulac-Sage P,Seror O,Blanc JF,Calderaro J,Deleuze JF,Imbeaud S,Zucman-Rossi J,Letouzé E
Evidence We also identified one tumor with HBV insertion and 3 tumors with AAV2 insertions in CCNA2. Finally, 6 tumors strongly overexpressed CCNA2 (FPKM > 15), 3 of which displayed 23鈥48 Mb intra-chromosomal deletions linking the intergenic region downstream CCNA2 with the highly expressed ALB, AFP, and ADH6 genes
Contents
Description
  • Site Information
Detail information of site [1005737]
  • Literature Information
The details of literature that this site is associated with.