Literature Information
PubMed PMID
|
27639803
|
Published year
|
2017 |
Journal
|
Gastroenterology |
Title
|
Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents. |
Author
|
Gao Q,Wang ZC,Duan M,Lin YH,Zhou XY,Worthley DL,Wang XY,Niu G,Xia Y,Deng M,Liu LZ,Shi JY,Yang LX,Zhang S,Ding ZB,Zhou J,Liang CM,Cao Y,Xiong L,Xi R,Shi YY,Fan J |
Evidence
|
Our patient-derived cell line-based model, integrating genetic and pharmacologic data from multiregional cancer samples, provides a platform to elucidate how intratumor heterogeneity affects sensitivity to different therapeutic agents.
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