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HIV Target gene Detail Information

> ST3GAL3 Gene Search Result


Gene Information
Gene Name ST3GAL3
Gene ID 6487
Gene Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 3
Gene Alias ST3N; MRT12; SIAT6; EIEE15; ST3GALII; ST3GalIII; ST3Gal III
Transcripts ENSG00000126091
Virus HIV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q11203
HGNC ID HGNC:10866
VEGA ID OTTHUMG00000007561
OMIM ID 606494
String ID 9606.ENSP00000262915
PharmGKB ID PA35768
Target gene [ST3GAL3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000872 chr1 44 92 124 260 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ST3GAL3 expression and immune infiltrating cell level correlation result in HIV+ samples
ST3GAL3 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ST3GAL3 expression and immune infiltrating cell level correlation result in HIV+ samples
ST3GAL3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).