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HBV Target gene Detail Information

> PRKG1 Gene Search Result


Gene Information
Gene Name PRKG1
Gene ID 5592
Gene Full Name protein kinase cGMP-dependent 1
Gene Alias PKG; cGK; AAT8; PKG1; cGK1; cGKI; cGK 1; PRKG1B; PRKGR1B; cGKI-BETA; cGKI-alpha
Transcripts ENSG00000185532
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Vesicles;
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q13976
HGNC ID HGNC:9414
VEGA ID OTTHUMG00000018248
OMIM ID 176894
String ID 9606.ENSP00000363092
PharmGKB ID PA33777
Target gene [PRKG1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003871 chr10 48 25 31 104 View
1012636 chr10 2 4 6 View
1016704 chr10 1 1 View
1016756 chr10 1 1 View
1017412 chr10 1 1 View
1018135 chr10 0 View
1019033 chr10 0 View
1019034 chr10 0 View
1100054 chr10 11 1 12 View
1100056 chr10 11 1 12 View
1100058 chr10 11 1 12 View
1100060 chr10 11 1 12 View
1100062 chr10 11 1 12 View
1100064 chr10 11 1 12 View
1100066 chr10 11 1 12 View
1100068 chr10 11 1 12 View
1100070 chr10 11 1 12 View
1100072 chr10 11 1 12 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PRKG1 expression and immune infiltrating cell level correlation result in HBV+ samples
PRKG1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).