HIV Target gene Detail Information

> PRDM2 Gene Search Result

Gene Information

Gene Name	PRDM2
Gene ID	7799
Gene Full Name	PR/SET domain 2
Gene Alias	RIZ; KMT8; RIZ1; RIZ2; KMT8A; MTB-ZF; HUMHOXY1
Transcripts	ENSG00000116731
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	Q13029
HGNC ID	HGNC:9347
VEGA ID	OTTHUMG00000007917
OMIM ID	601196
String ID	9606.ENSP00000235372
PharmGKB ID	PA33715

Target gene [PRDM2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000461	chr1	409	31	7	447	View
4000905	chr1	234	11	5	250	View
4002138	chr1	7	87	16	110	View
4005873	chr1	8	10	11	29	View
4005874	chr1	8	10	11	29	View
4006291	chr1	7	8	11	26	View
4006292	chr1	7	8	11	26	View
4006614	chr1	1	22		23	View
4006615	chr1	1	22		23	View
4008471	chr1	12	3		15	View
4008744	chr1	8	3	3	14	View
4009504	chr1	8	3		11	View
4009793	chr1	5	1	4	10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PRDM2 expression and immune infiltrating cell level correlation result in HIV+ samples
PRDM2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).