HIV Target gene Detail Information

> MEAF6 Gene Search Result

Gene Information

Gene Name	MEAF6
Gene ID	64769
Gene Full Name	MYST/Esa1 associated factor 6
Gene Alias	EAF6; CENP-28; C1orf149; NY-SAR-91
Transcripts	ENSG00000163875
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9HAF1
HGNC ID	HGNC:25674
VEGA ID	OTTHUMG00000004223
OMIM ID	611001
String ID	9606.ENSP00000362166
PharmGKB ID	PA165751536

Target gene [MEAF6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000291	chr1	170	322	89	581	View
4005192	chr1	30	5		35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MEAF6 expression and immune infiltrating cell level correlation result in HIV+ samples
MEAF6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MEAF6 expression and immune infiltrating cell level correlation result in HIV+ samples
MEAF6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).