HIV Target gene Detail Information

> DUS2 Gene Search Result

Gene Information

Gene Name	DUS2
Gene ID	54920
Gene Full Name	dihydrouridine synthase 2
Gene Alias	SMM1; DUS2L; URLC8
Transcripts	ENSG00000167264
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NX74
HGNC ID	HGNC:26014
VEGA ID	OTTHUMG00000137538
OMIM ID	609707
String ID	9606.ENSP00000455229
PharmGKB ID	PA142671937

Target gene [DUS2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006620	chr16	20	2	1	23	View
4009924	chr16	6		4	10	View
4009925	chr16	10			10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DUS2 expression and immune infiltrating cell level correlation result in HIV+ samples
DUS2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).