HIV Target gene Detail Information

> CHD1 Gene Search Result

Gene Information

Gene Name	CHD1
Gene ID	1105
Gene Full Name	chromodomain helicase DNA binding protein 1
Gene Alias	CHD-1; PILBOS
Transcripts	ENSG00000153922
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	O14646
HGNC ID	HGNC:1915
VEGA ID	OTTHUMG00000162744
OMIM ID	602118
String ID	9606.ENSP00000483667
PharmGKB ID	PA26451

Target gene [CHD1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000180	chr18	42	431	338	811	View
4001749	chr5	129	4	2	135	View
4003977	chr18	33	18		51	View
4004219	chr18	47			47	View
4008007	chr18	9	8		17	View
4010151	chr18	9			9	View
4010962	chr18	8			8	View
4012925	chr18	2	1	1	4	View
4013103	chr18	2		2	4	View
4014170	chr18	1	1		2	View
4014717	chr18	1	1		2	View
4014718	chr18	2			2	View
4014776	chr5	2			2	View
4016255	chr18				0	View
4100022	chr5	65			65	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CHD1 expression and immune infiltrating cell level correlation result in HIV+ samples
CHD1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CHD1 expression and immune infiltrating cell level correlation result in HIV+ samples
CHD1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).