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HBV Target gene Detail Information

> APOA2 Gene Search Result


Gene Information
Gene Name APOA2
Gene ID 336
Gene Full Name apolipoprotein A2
Gene Alias apoAII; Apo-AII; ApoA-II
Transcripts ENSG00000158874
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P02652
HGNC ID HGNC:601
VEGA ID OTTHUMG00000034346
OMIM ID 107670
String ID 9606.ENSP00000356969
Drugbank ID BE0000922
PharmGKB ID PA24886
Target gene [APOA2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003881 chr1 15 87 1 103 View
1003882 chr1 14 88 1 103 View
1006796 chr1 23 11 34 View
1006962 chr1 23 9 32 View
1007376 chr1 23 5 28 View
1007741 chr1 25 25 View
1007863 chr1 19 5 24 View
1008860 chr1 19 19 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of APOA2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
APOA2 expression: Low -> High
Lollipop of APOA2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of APOA2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of APOA2 expression and immune infiltrating cell level correlation result in HBV+ samples
APOA2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).