Virus Dataset Sample Info

> Dataset: 30307560 Search Result

Summary

Item	Summary
Project	30307560
Virus Name	HTLV1
Sample Number	38
Disease	Human T-cell lymphotropic virus type 1 (HTLV-1) and hepatitis B virus (HBV) coinfection
Country	Australia

Sample

ID	Sample ID	Age	Gender	Origin	Detail
1	Mono2	47	F	Australia	View
2	Mono4	54	M	Australia	View
3	Mono5	48	F	Australia	View
4	Mono6	54	M	Australia	View
5	Mono7	39	M	Australia	View
6	Mono9	55	F	Australia	View
7	Mono10	55	F	Australia	View
8	Mono11	38	F	Australia	View
9	Mono12	42	M	Australia	View
10	Mono13	62	M	Australia	View
11	Mono14	47	F	Australia	View
12	Mono15	36	M	Australia	View
13	Mono16	48	F	Australia	View
14	Mono17	65	M	Australia	View
15	Mono18	33	M	Australia	View
16	Mono19	29	M	Australia	View
17	Mono20	28	F	Australia	View
18	Mono21	46	M	Australia	View
19	Mono22	49	F	Australia	View
20	Mono23	57	M	Australia	View
21	Mono24	63	M	Australia	View
22	Mono25	48	M	Australia	View
23	Co1	48	F	Australia	View
24	Co2	64	F	Australia	View
25	Co3	60	F	Australia	View
26	Co4	61	M	Australia	View
27	Co5	55	M	Australia	View
28	Co6	54	F	Australia	View
29	Co7	54	F	Australia	View
30	Co8	63	M	Australia	View
31	Co9	61	M	Australia	View
32	Co10	54	M	Australia	View
33	Co11	49	F	Australia	View
34	Co12	62	M	Australia	View
35	Co13	51	M	Australia	View
36	Co14	64	M	Australia	View
37	Co15	64	M	Australia	View
38	Co16	51	M	Australia	View

Literature

Item	Summary
PMID	30307560
Title	Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia
Abstract	The prevalence of human T-cell lymphotropic virus type 1 (HTLV-1) and hepatitis B virus (HBV) coinfection is high in certain Indigenous Australian populations, but its impact on HTLV-1 has not been described. We compared 2 groups of Indigenous adults infected with HTLV-1, either alone or coinfected with HBV. The 2 groups had a similar HTLV-1 proviral load, but there was a significant increase in clonal expansion of HTLV-1-infected lymphocytes in coinfected asymptomatic individuals. The degree of clonal expansion was correlated with the titer of HBV surface antigen. We conclude that HTLV-1/HBV coinfection may predispose to HTLV-1-associated malignant disease.