Virus Dataset Sample Info

> Dataset: 27759101 Search Result

Summary

Sample

ID	Sample ID	Origin	Detail
1	Control-6	China	View
2	Control-27	China	View
3	Control-30	China	View
4	Control-31	China	View
5	Control-36	China	View
6	Control-54	China	View
7	Control-59	China	View
8	CIN1-16	China	View
9	CIN1-19	China	View
10	CIN1-34	China	View
11	CIN1-42	China	View
12	CIN1-43	China	View
13	CIN1-55	China	View
14	CIN1-61	China	View
15	CIN1-62	China	View
16	CIN2-4	China	View
17	CIN2-5	China	View
18	CIN2-11	China	View
19	CIN2-12	China	View
20	CIN2-16	China	View
21	CIN2-19	China	View
22	CIN3-2	China	View
23	CIN3-3	China	View
24	CIN3-4	China	View
25	CIN3-5	China	View
26	CIN3-6	China	View
27	CIN3-7	China	View
28	CIN3-8	China	View
29	CIN3-10	China	View
30	CIN3-12	China	View
31	CIN3-14	China	View
32	CIN3-15	China	View
33	CIN3-16	China	View
34	CIN3-17	China	View
35	CIN3-20	China	View
36	CIN3-21	China	View

Literature

Item	Summary
PMID	27759101
Title	Genome-wide Profiling of the Human Papillomavirus DNA Integration in Cervical Intraepithelial Neoplasia and Normal Cervical Epithelium by HPV Capture Technology
Abstract	HPV integration plays an important role in cervical carcinogenesis. HPV genotypes and the exact integration sites were investigated using HPV capture technology combined with next generation sequencing in 166 women. Three, one and six integration sites were verified in 7 HPV-positive 'normal cervical epithelium', 6 HPV-positive CIN2 and 15 HPV-positive CIN 3 samples, respectively. Of the 10 integrations, one and nine were involved with HPV33 and HPV16, respectively. Our study accurately evaluated HPV integration level in CINs and normal cervical tissues using high-throughput viral integration detection method providing basic evidence for HPV integration-driven cervical carcinogenesis.