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Virus Dataset Sample Info

> Dataset: 22815898 Search Result


Summary
Item Summary
Project 22815898
Virus Name HPV
Sample Number 87
Disease Cervical cancer
Country Mumbai

Sample
ID Sample ID Age Gender Origin Detail
1 CT 702 56 Mumbai View
2 CT 777 78 Mumbai View
3 CT 700 61 Mumbai View
4 CT 1123 45 Mumbai View
5 CT 709 32 Mumbai View
6 CT 809 70 Mumbai View
7 CT 712 68 Mumbai View
8 CT 1138 40 Mumbai View
9 CT 1194 55 Mumbai View
10 CT 866 41 Mumbai View
11 CT 864 44 Mumbai View
12 CT 733 61 Mumbai View
13 CT 718 57 Mumbai View
14 CT 739 70 Mumbai View
15 CT 892 56 Mumbai View
16 CT 785 42 Mumbai View
17 CT 755 50 Mumbai View
18 CT 1210 52 Mumbai View
19 CT 707 50 Mumbai View
20 CT 723 69 Mumbai View
21 CT 706 53 Mumbai View
22 CT 711 56 Mumbai View
23 CT 999 53 Mumbai View
24 CT 1114 42 Mumbai View
25 CT 819 55 Mumbai View
26 CT 959 58 Mumbai View
27 CT 1122 42 Mumbai View
28 CT 846 39 Mumbai View
29 CT 1117 54 Mumbai View
30 CT 893 62 Mumbai View
31 CT 1019 58 Mumbai View
32 CT 912 56 Mumbai View
33 CT 796 56 Mumbai View
34 CT 915 57 Mumbai View
35 CT 1160 64 Mumbai View
36 CT 889 45 Mumbai View
37 CT 1162 67 Mumbai View
38 CT 714 72 Mumbai View
39 CT 753 40 Mumbai View
40 CT 1202 50 Mumbai View
41 CT 821 87 Mumbai View
42 CT 859 48 Mumbai View
43 CT 837 40 Mumbai View
44 CT 716 56 Mumbai View
45 CT 1169 54 Mumbai View
46 CT 836 58 Mumbai View
47 CT 871 46 Mumbai View
48 CT 1183 70 Mumbai View
49 CT 744 50 Mumbai View
50 CT 896 45 Mumbai View
51 CT 976 35 Mumbai View
52 CT 763 60 Mumbai View
53 CT 927 44 Mumbai View
54 CT 1094 58 Mumbai View
55 CT 793 38 Mumbai View
56 CT 922 53 Mumbai View
57 CT 940 60 Mumbai View
58 CT 1215 55 Mumbai View
59 CT 914 61 Mumbai View
60 CT 848 68 Mumbai View
61 CT 1097 60 Mumbai View
62 CT 825 45 Mumbai View
63 CT 740 39 Mumbai View
64 CT 906 62 Mumbai View
65 CT 752 59 Mumbai View
66 CT 839 70 Mumbai View
67 CT 785 42 Mumbai View
68 CT 1170 60 Mumbai View
69 CT 918 45 Mumbai View
70 CT 1161 40 Mumbai View
71 CT 951 54 Mumbai View
72 CT 1108 54 Mumbai View
73 CT 887 51 Mumbai View
74 CT 934 44 Mumbai View
75 CT 1135 46 Mumbai View
76 CT 868 60 Mumbai View
77 CT 1107 55 Mumbai View
78 CT 828 66 Mumbai View
79 CT 800 56 Mumbai View
80 CT 1015 49 Mumbai View
81 CT 1082 55 Mumbai View
82 CT 905 49 Mumbai View
83 CT 787 45 Mumbai View
84 CT 935 67 Mumbai View
85 CT 792 60 Mumbai View
86 CT 759 65 Mumbai View
87 CT 1101 56 Mumbai View

Literature
Item Summary
PMID 22815898
Title HPV Genotyping and Site of Viral Integration in Cervical Cancers in Indian Women
Abstract Persistent HPV infection plays a major role in cervical cancer. This study was undertaken to identify HPV types in a cohort of Indian women with locally advanced cervical cancer as well as to determine the physical state and/or site of viral integration in the host genome. Pretreatment biopsies (n = 270) from patients were screened for HPV infection by a high throughput HPV genotyping assay based on luminex xMAP technology as well as MY09/11 PCR and SPF1/2 PCR. Overall HPV positivity was observed to be 95%, with HPV16 being most common (63%) followed by infection with HPV18. Integration status of the virus was identified using Amplification of Papillomavirus Oncogene Transcripts (APOT) assay in a subset of samples positive for HPV16 and/or HPV18 (n = 86) and with an adequate follow-up. The data was correlated with clinical outcome of the patients. Integration of the viral genome was observed in 79% of the cases and a preference for integration into the chromosomal loci 1p, 3q, 6q, 11q, 13q and 20q was seen. Clinical data revealed that the physical state of the virus (integrated or episomal) could be an important prognostic marker for cervical cancer.